منابع مشابه
Massive Splenomegaly
Hospital Physician May 2008 31 Splenomegaly is a common finding in a wide spectrum of diseases. Massive splenomegaly, however, always indicates underlying pathology. Massive splenomegaly is usually defined as a spleen extending well into the left lower quadrant or pelvis or which has crossed the midline of the abdomen. Massive spleens weigh at least 500 to 1000 g. In a retrospective study evalu...
متن کاملMassive splenomegaly in hairy cell leukemia.
n engl j med 367;22 nejm.org november 29, 2012 2133 A 63-year-old man presented with a 6-month history of fatigue, weight loss, and gingival bleeding. Physical examination suggested the presence of a massively enlarged spleen, a finding confirmed on a reconstructed coronal computed tomographic image of the abdomen (Panel A, arrowheads). A complete blood count revealed thrombocytopenia (platelet...
متن کاملPartial splenectomy for massive splenomegaly secondary to Gaucher's disease.
A 16 year old girl with Type 1 Gaucher's disease presented with massive splenomegaly, hypersplenism and abdominal discomfort. Traditionally hypersplenism has been treated with splenectomy, but this results in a high incidence of overwhelming sepsis and accelerated sphingolipid deposition in both liver and bone. A 90% partial splenectomy was therefore performed leaving a fully vascularized infer...
متن کاملGaucher’s Disease, an Unusual Cause of Massive Splenomegaly, a Case Report
Background Gaucher’s Disease (G.D.) is an autosomal recessive disorder resulting from the accumulation of glucocerebrosidase in the cells of macrophage-monocyte system as a result of a deficiency in lysosomal glucocerebrosidase. This enzyme is encoded by a gene on chromosome-1. Here we report a case of Gaucher’s Disease .G.D is rare in Yazd. Case reports We reported a patient that presented...
متن کاملSelf-assessment questions Massive splenomegaly in tropical West Africa
Case 1 A 32-year-old woman presented with lethargy and an abdominal mass which had been present for 3 years. On examination she had moderately pale conjunctivae but no jaundice or lymphadenopathy and there were no stigmata of chronic liver disease. A non-tender, massively enlarged, firm spleen was palpable 24 cm below the costal margin and there was hepatomegaly of 2 cm with no detectable ascit...
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ژورنال
عنوان ژورنال: BJS Open
سال: 2017
ISSN: 2474-9842
DOI: 10.1002/bjs5.1